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By Leonard S. Dreifus, Joel Morganroth (auth.), Leonard S. Dreifus, Albert N. Brest (eds.)

During the previous decade huge, immense development has been made within the improvement of recent cardiovascular medications and in our figuring out of the medical pharma­ cology and the pharmacokinetics of outdated medicines. moreover, more recent purposes of older brokers have emerged. for instance, vasodilators akin to nitroglycerin at the moment are being hired within the therapy of congestive middle failure, and anti­ hypertensives comparable to bretylium are utilized in the administration of ventricular arrhythmias. person chapters during this ebook concentrate on (1) the scientific pharmacology and pharmacokinetics of the person medications, and (2) the scientific purposes of those medicines, with realization additionally to serum concentrations, pathophysiology, and drug interactions the place applicable. The individuals to this article have worked to supply the reader with a significant, sensible replace at the medical makes use of and value of cardioactive medications. we're deeply thankful to every of them for his or her beneficiant participation during this recreation. LEONARD S. DREIFUS, M.D. ALBERT N. BREST, M.D. 1. ANTIARRHYTHMIC brokers LEONARD S. DREIFUS and JOEL MORGANROTH preferably, the administration of cardiac arrhythmias has to be predicated on (1) entire elucidation of the genesis of a number of the rhythm disturbances, and (2) a whole realizing of the pharmacologic motion of person antiarrhythmic brokers. purely with this unique details does it develop into attainable to manage a specific agent or brokers particularly potent opposed to a given arrhythmia.

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